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[目的]观察补肾活血汤联合西药治疗糖尿病肾病疗效。[方法]将45例患者随机分为治疗组24例和对照组21例。对照组给予单纯的使用降压药及降血糖药物治疗;治疗组在对照组治疗基础上配合补肾活血汤(药用水蛭粉、生地黄、益母草、葛根、生黄芪等),水煎服,3次/d。均以8周为1个疗程,治疗1疗程后判定疗效。[结果]对照组总有效率52.38%,治疗组总有效率66.67%,治疗组总有效率明显高于对照组(P<0.05)。两组24h尿蛋白排量均有下降的趋势,治疗组优于对照组(P<0.01)。治疗组空腹血糖、餐后2h血糖改善情况明显优于对照组(P<0.05)。[结论]补肾活血汤联合西药治疗糖尿病肾病疗效显著,值得临床推广应用。
[Objective] To observe the therapeutic effect of Bushen Huoxue Decoction combined with western medicine on diabetic nephropathy. [Method] 45 patients were randomly divided into treatment group (24 cases) and control group (21 cases). The control group was given pure antihypertensive drugs and hypoglycemic drugs; the treatment group was treated with Bushen Huoxue Decoction (medicinal leech powder, Herba Rehmanniae, Motherwort, Radix Puerariae, Radix Astragali), Shuijianbi, 3 Times / d. Eight weeks for a course of treatment, treatment after a course of treatment to determine efficacy. [Results] The total effective rate of the control group was 52.38%, and the total effective rate of the treatment group was 66.67%. The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). The urinary protein excretion in both groups tended to decrease, the treatment group was better than the control group (P <0.01). Fasting blood glucose in the treatment group, 2h postprandial blood glucose was significantly better than the control group (P <0.05). [Conclusion] Bushen Huoxue Decoction combined with Western medicine has a significant therapeutic effect on diabetic nephropathy and is worthy of clinical application.