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为观察和分析重症严重急性呼吸综合征(severeacuterespiratorysyndrome,SARS)患者的临床特点及其影响因素,对我院收治的149例重症SARS患者进行回顾性分析,分别观察患者的一般情况、临床表现、化验指标、肺部阴影、心电图变化、各种治疗情况及预后。结果149例重症SRAS患者中男女比例相当,年龄多于25～75岁之间,40.3%合并慢性基础病,96.0%患者发热,58.0%外周血白细胞正常或降低,78.7%淋巴细胞减少,60%以上血生化多种酶升高,46.9%白蛋白/球蛋白(A/G)比值降低,37.6%血糖(GLU)升高,53.1%患者有低氧血症,81.8%肺损伤面积大,31.7%有心电图异常,58.7%有并发症。主要治疗包括糖皮质激素、抗生素、抗真菌药、抗病毒药、免疫增强剂、中药、吸氧和呼吸机辅助呼吸及支持疗法。最终痊愈和好转患者130人(占87.2%),死亡19人(12.8%)。提示高龄、合并基础疾病和并发症、肺损伤面积大、低氧血症严重、血生化改变大的患者病情重、病死率高。
In order to observe and analyze the clinical features and influencing factors of severe acute respiratory syndrome (SARS), 149 severe SARS patients admitted to our hospital were retrospectively analyzed. The general situation, clinical manifestations, laboratory tests Indicators, lung shadow, electrocardiogram changes, a variety of treatment and prognosis. Results A total of 149 patients with severe SRAS had similar proportions of men and women, older than 25-75 years, 40.3% with chronic basis disease, 96.0% with fever, 58.0% with normal or decreased peripheral white blood cells, 78.7% with lymphopenia, 60% The above blood biochemical enzymes increased, the ratio of 46.9% albumin / globulin (A / G) decreased, 37.6% elevated blood glucose (GLU), 53.1% had hypoxemia, 81.8% % ECG abnormalities, 58.7% have complications. The main treatments include glucocorticoids, antibiotics, antifungals, antivirals, immune boosters, herbs, oxygen and ventilator-assisted breathing and supportive therapies. The final recovery and improvement of 130 patients (87.2%), 19 people died (12.8%). Prompted elderly, combined with underlying diseases and complications, lung injury area, severe hypoxemia, blood biochemical changes in patients with heavy illness, high mortality.