为观察肝炎肝硬化患者的血浆神经肽Y水平 ,采用放射免疫法检测了 5 6例肝炎肝硬化患者血浆神经肽Y浓度。结果显示 ,所测患者神经肽Y浓度均高于正常人 ,差异有显著性 (P <0 0 5～ 0 0 1)。伴有腹水者显著高于无腹水者 ,腹水经治疗消失后 ,神经肽Y浓度下降 ,但仍高于正常人 ;神经肽Y血浆水平与肝功能分级亦有相关性 ,提示神经肽Y在肝硬化及其某些并发症发生过程中可能起作用 To observe the level of plasma neuropeptide Y in cirrhotic patients with hepatitis, radioimmunoassay was used to detect plasma neuropeptide Y concentrations in 56 patients with cirrhosis of liver. The results showed that the concentration of neuropeptide Y were higher than normal, the difference was significant (P <0 05 ~ 0 0 1). Patients with ascites were significantly higher than those without ascites, ascites disappeared after treatment, neuropeptide Y concentration decreased, but still higher than normal; neuropeptide Y plasma levels and liver function classification are also related, suggesting that neuropeptide Y in the liver Sclerosis and some of its complications may play a role in the process