Wegener肉穿肿病以上皮样引起坏死的肉芽肿和累及小动脉的播散性血管炎为特征。它最先侵袭肺和肾，但任何器官系统都可被侵犯，大约1／3患者表现为局部型。有19～45％的患者在病程中的某个时候发生耳病，包括浆液性中耳炎，感音神经性听力损失和慢性中耳炎。局邢型诊断困难，因 Wegener’s disease is characterized by necrotic granulomas and disseminated vasculitis involving the arterioles in the epithelium. It first attacks the lungs and kidneys, but any organ system can be violated, and about one third of patients experience localized disease. 19-45% of patients develop the disease at some time during their course of disease, including serous otitis media, sensorineural hearing loss and chronic otitis media. Bureau Xing type diagnosis difficult, because