1991～1994年,我们对26例大脑恶性胶质瘤病人采用超选择性动脉内注入卡氮芥化疗,效果满意。1 临床资料 本组病人均经手术及病理证实。年龄5～58岁。肿瘤位于大脑半球22例,丘脑区和侧脑室内各2例。星形胶质细胞瘤19例,胶质母细胞瘤1例,恶性室管膜细胞瘤2例,少枝胶质细胞瘤4例。化疗前行肿瘤次全和大部切除22例,部分切除4例。化疗后出现头痛10例,消化道症状8例,偏瘫加重2例,癫痫发作1例。 From 1991 to 1994, 26 patients with malignant gliomas were treated with hyper-selective intra-arterial infusion of Carbazone, with satisfactory results. 1 clinical data of this group of patients were confirmed by surgery and pathology. Age 5 to 58 years old. The tumor was located in the cerebral hemisphere in 22 cases, in the thalamus and lateral ventricle in 2 cases. There were 19 cases of astrocytoma, 1 case of glioblastoma, 2 cases of malignant ependymoma and 4 cases of less glioblastoma. Tumor before subtotal and most resection in 22 cases, partial resection in 4 cases. After chemotherapy, 10 cases of headache, gastrointestinal symptoms in 8 cases, hemiplegia aggravated in 2 cases, 1 case of epileptic seizures.