病毒性肝炎常引起暂时性血细胞生成的异常,一般在临床上并没有很大意义。但在个别病例可以很严重,甚至可造成患者死亡。有关病毒性肝炎引起的各种血液学障碍的报导中,粒性白细胞缺乏症是比较少见的。作者报导两例病毒性肝炎引起的粒性白细胞缺乏症病例。患者的骨髓象均表现出细胞增生。病毒性肝炎引起的血液学改变有质和量两方面的变化。量的改变较常见,包括早期的白细胞减少,血小板减少,全血细胞减少与再生障碍性贫血。质的改变较少见,包括不典型的淋巴细胞,巨红细胞增多,红细胞寿命缩短和溶血性贫血。这些血细胞生成异常的发病机制大部分尚未弄清楚。有各种假设,包括自家免疫机制、肝脏对一些骨髓抑制物质的解毒功能发生障碍、以及病毒对骨髓的毒性作用等。Boxer等于一名伴有白细胞减少的慢性 Often caused by viral hepatitis transient hematopoiesis, usually not clinically significant. However, individual cases can be severe and can even cause death. Of the various hematological disorders caused by viral hepatitis reported, granulocytic leukemia is relatively rare. The authors report two cases of viral hepatitis caused by granulocytic leukemia cases. The bone marrow of patients showed cell proliferation. Hemological changes caused by viral hepatitis have both qualitative and quantitative changes. Changes in volume are more common, including early leukopenia, thrombocytopenia, pancytopenia and aplastic anemia. Less common qualitative changes, including atypical lymphocytes, macrophages, shortened life span of red blood cells and hemolytic anemia. Most of the pathogenesis of these abnormalities of hematopoiesis has not yet been clarified. There are various assumptions, including its own immune mechanisms, the liver’s detoxification of some of the substances inhibit bone marrow dysfunction, as well as the virus on the bone marrow toxicity and so on. Boxer is equal to a chronic with leukopenia