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目的:探究应用匹多莫德口服液对口腔盘状红斑狼疮的治疗效果。方法:选取近两年在我院接受治疗的口腔盘状红斑狼疮患者80例,随机分为对照组40人,试验组40人,对照组进行硫酸羟氯喹片治疗,试验组进行匹多莫德口服液治疗,观察并比较两组患者经不同方式后的治疗效果。结果:试验组治疗后的总有效率(90.00%)明显高于对照组治疗后的总有效率(62.50%),两组有显著性差异,统计学上有意义(P<0.05)。结论:匹多莫德口服液治疗口腔盘状红斑狼疮中,可以有效缩小患者的黏膜病变面积,缓解患者的自觉症状。
Objective: To investigate the therapeutic effect of Pidotimod oral solution on oral discoid lupus erythematosus. Methods: Eighty patients with oral discoid lupus erythematosus (SLE) treated in our hospital in recent two years were randomly divided into control group (40), test group (40) and control group (treated with hydroxychloroquine sulfate tablets) Oral liquid treatment, observation and comparison of the two groups of patients after treatment by different ways. Results: The total effective rate (90.00%) after treatment in the experimental group was significantly higher than that in the control group (62.50%) after treatment. There was a significant difference between the two groups (P <0.05). Conclusion: Pidotimod oral solution in the treatment of oral discoid lupus erythematosus, can effectively reduce the mucosal lesions in patients with alleviating the patient’s symptoms.