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目的探讨肝硬化伴消化道功能障碍患者采用酸化肠道的治疗方式对血氨水平的影响。方法 68例肝硬化伴消化道功能障碍患者,随机分为对照组和观察组,各34例。对照组采用常规治疗,观察组在常规治疗基础上加用酸化肠道治疗,比较两组患者治疗前后血氨水平及治疗总有效率。结果治疗后观察组患者血氨水平(36.20±8.28)μmol/L低于对照组(48.61±13.55)μmol/L;观察组治疗总有效率为79.4%高于对照组的55.9%,差异均有统计学意义(P<0.05)。结论对肝硬化伴消化道功能障碍患者采用酸化肠道的治疗方式可以明显降低患者血氨水平,提高患者治疗效果,值得临床推广。
Objective To investigate the effect of acidified intestinal tract treatment on serum ammonia level in patients with cirrhosis and gastrointestinal dysfunction. Methods Sixty-eight patients with cirrhosis and gastrointestinal dysfunction were randomly divided into control group and observation group, with 34 cases in each group. The control group was treated by conventional therapy. The observation group was treated with acidizing intestinal tract on the basis of conventional treatment. The levels of serum ammonia and the total effective rate of treatment were compared between the two groups before and after treatment. Results After treatment, the level of serum ammonia (36.20 ± 8.28) μmol / L in the observation group was lower than that in the control group (48.61 ± 13.55) μmol / L. The total effective rate in the observation group was 79.4%, which was higher than that in the control group (55.9% Statistical significance (P <0.05). Conclusion The treatment of acidified intestinal tract in patients with cirrhosis and gastrointestinal dysfunction can significantly reduce the blood ammonia level and improve the therapeutic effect of patients, which deserves clinical promotion.