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第三脑室注射微量强啡肽抗血清,对大鼠ACTH和催乳素的静息分泌无明显影响;但抑制限制性应激时ACTH和催乳素的释放,抑制率分别为63.0％和67.3％。提示脑内源性强啡肽可能是应激时ACTH和催乳素平行释放的重要调制因子。
The third ventricle injection of micro-dynorphin antiserum had no effect on the resting secretion of ACTH and prolactin in rats. However, the inhibitory rates of ACTH and prolactin were 63.0% and 67.3%, respectively. Tip brain endogenous dynorphin may be stress when ACTH and prolactin parallel release of important modulators.