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目的评估晚期早产儿生后早期神经发育情况。方法选择本院新生儿科2015年1月至2015年12月收治的171例晚期早产儿为观察对象,同时选择同期新生儿科收治的145例足月儿为对照组。所有研究对象在校正胎龄40周、3月龄、6月龄及1周岁时进行测试,比较神经发育水平。结果校正胎龄40周龄时,晚期早产儿和足月儿NBNA评分差异无统计学意义(P>0.05);3月龄时晚期早产儿大运动落后于足月儿;6月龄时晚期早产儿大运动、精细动作、语言落后于足月儿;1周岁时精细动作落后于足月儿,差异均有统计学意义(P<0.05)。结论晚期早产儿神经发育欠佳,生后早期需加强监护和随访并进行针对性干预。
Objective To evaluate the early postnatal neurodevelopment in advanced preterm infants. Methods One hundred and seventy-one premature infants who were admitted to our neonatology department from January 2015 to December 2015 were enrolled in this study. 145 full-term infants were selected as the control group. All subjects were tested for gestational age 40 weeks, 3 months, 6 months and 1 year old to compare the level of neurodevelopment. Results There was no significant difference in NBNA score between preterm and term infants at 40 weeks of gestational age correction (P> 0.05) Children’s grand movement, fine movement, language lag in full-term children; 1 year old fine motor lagging behind full-term children, the difference was statistically significant (P <0.05). Conclusions The neurodevelopment in the late preterm infants is not good. Care and follow-up should be strengthened in the early postnatal period and targeted intervention should be carried out.