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目的分析原发性胃淋巴瘤预后与各临床病理因素及治疗的关系。方法随访该院33年间因原发性胃淋巴瘤接受手术治疗的病人,用Kaplan-Meier生存时间分析、COX多因素分析研究生存预后与各临床病理因素以及治疗的关系。结果整体3年存活率为85%,5年存活率为67.24%。手术+化疗3年存活率为86.35%,5年存活率为82.43%。细胞分级、周围器官或远处转移、手术方式、术后是否化疗是原发性胃淋巴瘤的独立预后因子,其他临床病理因素与原发性胃淋巴瘤预后尚无显著相关。结论胃淋巴瘤的治疗应以手术、化疗为主,化疗可能更为重要,联合应用可以获得较满意的效果。根据细胞分级、周围器官或远处转移、手术方式、术后是否化疗可以预测原发性胃淋巴瘤的预后。
Objective To analyze the relationship between the prognosis of primary gastric lymphoma and the clinicopathological factors and treatment. Methods Patients were followed up for 33 years due to primary gastric lymphoma in this hospital. Kaplan-Meier survival time analysis and COX multivariate analysis were used to investigate the relationship between prognosis and clinicopathologic factors and treatment. Results The overall 3-year survival rate was 85%, 5-year survival rate was 67.24%. The 3-year survival rate of surgery + chemotherapy was 86.35%, and the 5-year survival rate was 82.43%. Cell classification, peripheral organs or distant metastases, surgical procedures, postoperative chemotherapy is an independent prognostic factor for primary gastric lymphoma, and other clinical and pathological factors and primary gastric lymphoma prognosis was not significantly correlated. Conclusion The treatment of gastric lymphoma should be based on surgery and chemotherapy. Chemotherapy may be more important, and combined application can achieve more satisfactory results. According to cell classification, peripheral organs or distant metastases, surgical methods, whether postoperative chemotherapy can predict the prognosis of primary gastric lymphoma.