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目的 探讨肝癌射频消融治疗的有效性和安全性。方法 对216例肝癌共行252次射 频消融治疗,观察射频消融治疗后病人的不良反应、肝功能、甲胎蛋白(AFP)水平、肿瘤血供变化、CT 影像学变化及1年生存率。结果 射频消融治疗后病人的不良反应发生率为82%,56%的病人有轻 度的转氨酶升高,射频消融治疗前AFP升高者有85%的病人有程度不同的下降。76%的病人射频消 融治疗后彩色多普勒超声观察肿瘤血供明显减少或消失。射频消融治疗后1～6个月肝脏增强CT 扫描全部病人均有程度不同的肿瘤液化坏死,不强化者占56%,病人1年生存率为84%。结论 射 频消融是治疗肝癌的一种安全有效的方法。
Objective To investigate the effectiveness and safety of radiofrequency catheter ablation in liver cancer. Methods Totally 252 radiofrequency ablation radiosurgery were performed in 216 patients with hepatocellular carcinoma. The adverse reactions, liver function, AFP level, tumor blood supply, CT imaging changes and 1-year survival rate after radiofrequency ablation were observed. Results The incidence of adverse reactions was 82% in patients undergoing radiofrequency ablation, with mild transaminase elevation in 56% of patients and varying degrees of decline in 85% of patients with elevated AFP before radiofrequency ablation. 76% of patients after radiofrequency ablation treatment of color Doppler ultrasound showed significant reduction or disappearance of blood supply to the tumor. 1 ~ 6 months after radiofrequency ablation, all patients had different degrees of tumor liquefaction necrosis, 56% did not strengthen, and 1 year survival rate was 84%. Conclusion Radiofrequency ablation is a safe and effective method for the treatment of liver cancer.