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选择高血压病合并缺血性心、脑血管病患者70例,依合并症分为2组,各35例。患者服用依那普利5～20毫克/日,合并冠心病组联合服用地尔硫黄45～240毫克/日;合并脑血管病组联合服用尼莫地平90～180毫克/日。经6周治疗,两组总有效率分别为92％和88％,平均血压下降显著(P<0.01)。两组之间总有效率经Ridit分析无显著差异(P>0.05),合并症大多数患者有不同程度的改善,不良反应轻微。
Seventy patients with hypertension and ischemic heart and cerebrovascular disease were selected and divided into two groups according to the complication: 35 cases each. Patients taking enalapril 5 to 20 mg / day, combined coronary heart disease combined with diltiazem 45 ~ 240 mg / day; combined cerebrovascular disease group taking nimodipine 90 ~ 180 mg / day. After 6 weeks of treatment, the total effective rate was 92% and 88% in both groups, mean blood pressure decreased significantly (P <0.01). There was no significant difference (P> 0.05) in total effective rate between the two groups by Ridit analysis. Most patients with comorbidities had some degree of improvement with mild adverse reactions.