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高血压是肾功能不全最常见的并发症之一,它可加速肾衰和心血管病的发展,这些都是透析病人和肾移植病人的主要死亡原因。近已报告钙离子拮抗剂硝苯吡啶对治疗高血压及高血压危象有效,但对治疗肾功能不全高血压的资料报告甚少。本文分别用硝苯吡啶胶囊10mg(10例)和片剂20mg(15例)一次口服来观察二组慢性肾功能不全(肌酐清除率10～40ml/min)高血压病者的急性降压作用。用慢释放硝苯吡啶片剂口服观察另外25例慢性肾功能
Hypertension, one of the most common complications of renal insufficiency, accelerates the development of renal failure and cardiovascular disease, all of which are major causes of death in dialysis and kidney transplant patients. It has been reported that nifedipine, a calcium ion antagonist, is effective in treating hypertension and hypertensive crisis, but little is reported about the treatment of renal insufficiency hypertension. In this paper, nifedipine capsules 10mg (10 cases) and tablets 20mg (15 cases) were taken orally to observe the two groups of chronic renal insufficiency (creatinine clearance 10 ~ 40ml / min) of hypertensive patients with acute antihypertensive effect. Another 25 patients with chronic renal failure were orally observed with slow-release nifedipine tablets