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为了解北京市不同大气铅浓度地区新生儿脐带血铅水平，在北京市选择最高及最低大气铅浓度地区，收集所在区各1所医院新生儿脐带血标本256份（227份有效），用原子吸收分光仪石墨炉法测定铅含量，并严格执行质量控制，比较两地区新生儿脐带血铅水平。结果，高大气铅浓度地区比低大气铅浓度地区新生儿脐带血血铅水平高（t=2．31，P＜0.05），两地区新生儿脐血铅≥0．483μmol／L的比例无显著差异，≥0．338μmol／L的比例有增高趋势。经多元logistic回归分析发现，居室邻近马路、孕早期上呼吸道感染为高大气铅浓度地区胎儿期铅暴露的危险因素。结论，北京市大气铅污染可能是胎儿期铅暴露的危险因素之一。
In order to understand the cord blood lead levels of newborns in different atmospheric lead concentrations in Beijing, 256 cord blood samples (227 validated) were collected from one hospital in each district in Beijing, choosing the highest and lowest atmospheric lead concentrations. Absorption spectrometer graphite furnace method for the determination of lead content and strict implementation of quality control, comparison of cord blood lead levels in newborns in both regions. As a result, cord blood levels were higher in neonates with high-level of lead than those of low-level of lead (t = 2.31, P <0.05), and no significant difference in neonatal cord blood levels of 0.483 μmol / L Difference, ≥0.338μmol / L the proportion of increasing trend. Multivariate logistic regression analysis showed that upper respiratory tract infection in the neighborhood of the room and in the first trimester of pregnancy was a risk factor for fetal lead exposure in high-level lead concentrations. Conclusions: Atmospheric lead pollution in Beijing may be one of the risk factors of fetal lead exposure.