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目的观察探讨盐酸氟桂利嗪预防性治疗偏头痛性眩晕的疗效。方法选取临床确诊的偏头痛性眩晕患者46例,将其分为观察组及对照组。观察组给予盐酸氟桂利嗪胶囊(10mg,QN)+甲磺酸培他司汀片(6mg,TID)联合口服;对照组给予甲磺酸培他司汀片(6mg,tid)单独口服。观察开始治疗3个月内头痛和眩晕发作的严重程度和发作的次数。结果治疗后3个月内,观察组较对照组在头痛发和眩晕发作的程度和次数上均有有明显减轻,差异具有统计学意义(P>0.05)。结论盐酸氟桂利嗪预防性治疗偏头痛性眩晕具有明确疗效。
Objective To investigate the efficacy of flunarizine hydrochloride in the prevention and treatment of migraine headache. Methods 46 patients with clinically diagnosed migraine vertigo were divided into observation group and control group. The observation group was treated with Flunarizine Hydrochloride Capsule (10mg, QN) + Pentostatl mesylate tablets (6mg, TID) orally. The control group was given pravastatin mesylate tablet (6mg, tid) orally alone. The severity of headache and vertigo episodes and the number of seizures were observed within 3 months of starting treatment. Results Within 3 months after treatment, the observation group had a significant reduction in the degree and number of headache and vertigo episodes compared with the control group, the difference was statistically significant (P> 0.05). Conclusion Flunarizine hydrochloride has a definite curative effect on prophylactic treatment of migraine headache.