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目的：评价ＳＰＥＣＴ脑血流灌注显像在癫痫病灶定位诊断中的价值。方法：对９６例癫痫间歇期、１３例发作期患者进行了ＳＰＥＣＴ脑血流灌注显像，９３例作了ＥＥＧ检查，７４例作了脑ＣＴ检查，２５例作了ＭＲＩ检查。并对各种检测的结果进行比较。结果：ＳＰＥＣＴ脑血流灌注显像对癫痫病灶的检出阳性率为９７２５％，其它方法检出的阳性率ＥＥＧ为８６０２％，ＭＲＩ为３６％，ＣＴ为２７０３％。ＳＰＥＣＴ与ＥＥＧ阳性检出符合率为８３８７％。ＣＴ、ＭＲＩ和ＳＰＥＣＴ检出的病灶部位符合率分别为６２５％和５６％。ＳＰＥＣＴ脑血流灌注显像检出的癫痫病灶８５％分布在大脑颞叶、额叶和顶叶。５５％以上的癫痫患者有２个或２个以上的癫痫灶。结论：ＳＰＥＣＴ脑血流灌注显像是诊断癫痫病灶的灵敏而有效的方法，对制定癫痫的手术或γ刀治疗方案具有重要意义，其对癫痫病灶的定位价值优于ＥＥＧ、ＭＲＩ和ＣＴ。
Objective: To evaluate the value of SPECT perfusion imaging in the localization of epilepsy lesions. Methods: Ninety-six patients with intermittent epilepsy and 13 with exacerbation underwent SPECT cerebral perfusion imaging. EEG examination was performed in 93 cases, brain CT examination in 74 cases and MRI examination in 25 cases. The results of various tests were compared. Results: The positive rate of detection of epilepsy by SPECT was 97.25%. The positive rates of other methods were 86.02%, 36% for MRI and 27.3% for CT. The positive coincidence rate of SPECT and EEG was 8387%. The coincidence rates of lesions detected by CT, MRI and SPECT were 625% and 56% respectively. 85% of the epilepsy lesions detected by SPECT cerebral perfusion imaging are located in the temporal lobe, frontal lobe and parietal lobe. More than 55% of epilepsy patients have 2 or more epileptic foci. Conclusion: SPECT perfusion imaging is a sensitive and effective method for the diagnosis of epileptic foci. It is of great significance for the development of surgical or gamma knife treatment of epilepsy. Its location value in epileptic foci is superior to that of EEG, MRI and CT.