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在４只家兔同时进行每只８组药物点和２组对照点的２２．５Ｇｙ／ｃｍ２一次性９０Ｓｒβ照射后，分别于２４ｈ、７２ｈ，、１２０ｈ和１９２ｈ、取全层皮标本，单盲法病理切片观察受照射皮肤，用打分法评价介入药物对皮肤辐射损伤的影响．初步结果：早期效应以无菌性炎症反应为主，深度达表皮和真皮浅层。介入Ⅳ（２０１．２５分）、Ⅷ（１６７．５分）、Ⅴ（１６５分）、Ⅰ（１５０分），损伤分值高，其中Ⅳ与对照组（１５７．５、１４１．２５分）有显著性差异（Ｐ＜０·０５），即有辐射增敏作用，可用于敷贴中心．其它几组与对照组无显著性差异（Ｐ＞０．０５）．而介入Ⅲ损伤分值最低（１０７．５分）与对照组４有显著性差异（Ｐ＜０．０５），有增强皮肤抗辐射早期损伤的作用。
Four rabbits were treated with 22.5Gy / cm2 once-only 90Srβ irradiation at 8 drug points and 2 control points at the same time. Whole-thickness skin specimens were obtained at 24h, 72h, 120h and 192h respectively. Pathological observation of irradiated skin, using scoring method evaluation of interventional drugs on the skin radiation damage. Preliminary results: The early effects of aseptic inflammation, the depth of the epidermis and dermal superficial. Interventional Ⅳ (201.25 points), Ⅷ (167.5 points), Ⅴ (165 points), Ⅰ (150 points), the injury score was high, which Ⅳ and the control group (157.5,141.25 points) Significant difference (P <0 · 05), that is, the role of radiation sensitization, can be used for dressing centers. Other groups and the control group no significant difference (P> 0.05). However, the lowest intervention score (107.5 points) was significantly different from that of control group 4 (P <0.05), which could enhance the early anti-radiation injury of the skin.