动脉粥样硬化(Atherosclerosis 简称 AS)是一种多因素引起的疾病,近年来对 AS 发病原理的研究有了较大的进展。因此,筛选抗 AS 新药的途径也有了新的设想:一、从脂质代谢与 AS 的关系看抗 AS 药物的筛选脂质代谢紊乱与 AS 发病的关系仍是当前研究 AS 发病原理的首要问题。高胆固醇血症是 AS 的主要危险因素。因此凡对外源性胆固醇吸收抑制;加速体内胆固醇的排出 Atherosclerosis (Atherosclerosis referred to as AS) is a multifactorial disease, in recent years, the pathogenesis of AS have made great progress. Therefore, the screening of anti-AS drugs also have a new way of thinking: First, the relationship between lipid metabolism and AS anti-AS drug screening Lipid metabolism disorders and the relationship between the pathogenesis of AS is still the current study of the principle of the first issue. Hypercholesterolemia is a major risk factor for AS. Therefore, the absorption of exogenous cholesterol inhibition; speed up the body’s cholesterol emissions