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目的观察中药宫瘤清与射频消融对子宫肌瘤治疗后子宫及肌瘤体积缩小情况和血清雌、孕激素变化,为临床子宫肌瘤治疗探索一条新的治疗途径。方法2003年10月至2005年10月于安阳地区医院及新乡医学院三附院就诊的42例子宫肌瘤患者,根据患者手术意愿分为两组:①宫瘤清治疗组:20例子宫肌瘤患者给予宫瘤清胶囊治疗3个月,观察治疗前和治疗后1个月、3个月子宫及肌瘤体积及治疗前和治疗后3个月血清雌激素(estrogen,E2)、孕激素(progesterone,P)变化;②射频消融治疗组:22例子宫肌瘤患者给予射频消融保守治疗,治疗前及治疗后1个月、3个月观察指标同前。结果宫瘤清与射频消融对子宫肌瘤治疗均可使子宫及肌瘤体积缩小,观察其治疗后3个月情况,射频消融治疗组较宫瘤清治疗组子宫及肌瘤体积缩小更为明显(P<0.05),而且血清雌、孕激素均无变化(P>0.05)。结论射频消融治疗较宫瘤清治疗显效更快,对机体副作用更小,值得临床应用和推广。
Objective To observe the shrinkage of uterine fibroids and estrogen and progesterone in uterine leiomyoma treated with traditional Chinese medicine Gong Mi Qing and radiofrequency ablation, and to explore a new therapeutic approach for the treatment of uterine fibroids. Methods From October 2003 to October 2005, 42 patients with uterine leiomyoma treated in Anyang Hospital and Third Affiliated Hospital of Xinxiang Medical College were divided into two groups according to their intention of surgery: ① Gongyeqing treatment group: 20 cases of uterine muscle Patients with tumor were treated with Gongyuqing capsule for 3 months. The volume of uterus and fibroids before treatment, 1 month after treatment and 3 months before treatment and 3 months after treatment were observed. Serum estrogen (E2), progesterone (progesterone, P) changes; radiofrequency ablation treatment group: 22 cases of uterine fibroids conservative radiofrequency ablation treatment before treatment and 1 month after treatment, 3 months the same as the previous observation indicators. Results Palace tumor clearance and radiofrequency ablation of uterine fibroids can reduce the size of the uterus and fibroids, to observe the situation after 3 months of treatment, radiofrequency ablation treatment group than the palace tumor treatment group uterine and fibroids volume is more obvious (P <0.05), but there was no change in serum estrogen and progesterone (P> 0.05). Conclusion Radiofrequency ablation is faster and more effective than Gongyeqing treatment and has less side effects on the body, which is worthy of clinical application and promotion.