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本文报道1例甲状旁腺癌患者,可能由于肿瘤梗死而出现暂时的自发性生化缓解。患者男性,60岁。因腰痛、踝部浮肿及体重下降而就诊。体检除先天性杵状指外余均正常。血钙15mg%,血磷2.9mg%,硷性磷酸酶150 IU/L,血尿素23mg%,甲状旁腺激素(免疫测定法)(iPTH)13.1μg/L(正常0.8μg/L)。X线检查示指骨骨膜下侵蚀和“橄榄球运动衫”样脊柱。上述发现提示原发性甲状旁腺功能亢进。行颈部探查术,在左下颈部发现2.5cm×2.5cm×2cm并有包膜的棕褐色肿瘤,肿瘤由主细胞组成,虽然细胞外形规则,但偶而可见核有丝分裂,提示可能为甲状旁腺癌。术后血钙及iPTH
This article reports a case of parathyroid cancer in patients with possible temporary spontaneous biochemical remission due to tumor infarction. Male patient, 60 years old. Due to low back pain, ankle edema and weight loss and treatment. Except for congenital clubbing physical examination are more than normal. Blood calcium 15 mg%, phosphorus 2.9 mg%, alkaline phosphatase 150 IU / L, blood urea 23 mg%, parathyroid hormone (immunoassay) (iPTH) 13.1 μg / L (normal 0.8 μg / L). X-ray examination showed subperiosteal erosion of the phalanges and “Rugby Jersey” spine. The above findings suggest primary hyperparathyroidism. Neck exploration, found in the lower left neck 2.5cm × 2.5cm × 2cm and enveloped tan tumors, the tumor by the main cells, although the rules of the cell shape, but occasionally visible mitotic, suggesting that may be parathyroid cancer. Postoperative serum calcium and iPTH