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无环鸟苷是人类疱疹病毒族中所有5种病毒DNuA多聚酶特异的抑制剂,治疗许多疱疹病毒性疾病有效,为原发性和复发性生殖器疱疹、疱疹性脑炎及免疫损伤宿主的粘膜皮肤单纯疱疹病毒(HSV)感染首选药物。但用无环鸟苷治疗带状疱疹争论较大,因水痘-带状疱疹病毒对无环鸟苷的敏感性只有HSVⅡ型的1/10。故如应用,则开始需用大剂量静注1500mg/m~2/d,5～7天。它对免疫损伤的宿
Acyclovir is a specific inhibitor of all five DNuA polymerase in the human herpes virus family and is effective in the treatment of many herpes viral diseases, both for primary and recurrent genital herpes, herpes encephalitis, and mucosal skin of immunocompromised hosts Herpes simplex virus (HSV) drug of choice. However, the treatment of herpes zoster with acyclovir controversy, because varicella-zoster virus sensitivity to acyclovir only HSV Ⅱ type 1 / Therefore, if the application, then the need for high-dose intravenous infusion of 1500mg / m ~ 2 / d, 5 to 7 days. It’s immune damage to the sink