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目的:观察腹腔镜卵巢打孔术(LOD)联合中药治疗多囊卵巢综合症(PCOS)不孕的疗效。方法:选取2010年1月~2012年6月因PCOS不孕行LOD治疗的48例患者为LOD组,同时选择2012年7月~2014年12月PCOS不孕行LOD+中药治疗的50例患者为LOD+中药组,观察两组术后6个月内的排卵率和术后1年内的妊娠率。结果:LOD+中药组排卵率为86.00%(258/300)、妊娠率70.00%(35/50),LOD组排卵率为68.05%(196/288)、妊娠率为47.92%(23/48),两组比较,差异有统计学意义(χ2=4.48、4.94,P均<0.05)。结论:PCOS不孕LOD术后半年内及时利用内分泌环境的改善,辅以补肾、健脾、祛痰、调经中药,可提高PCOS不孕患者的排卵率和妊娠率。
Objective: To observe the efficacy of laparoscopic ovarian drilling (LOD) combined with traditional Chinese medicine treatment of polycystic ovary syndrome (PCOS) infertility. Methods: From January 2010 to June 2012, 48 patients with LOD treated by PCOS infertility were selected as LOD group. Fifty patients undergoing PCOS infertility with LOD + TCM from July 2012 to December 2014 were selected as LOD + TCM group, the ovulation rate within 6 months after operation and the pregnancy rate within 1 year after operation were observed. Results: The ovulation rate in LOD + TCM group was 86.00% (258/300), pregnancy rate was 70.00% (35/50), LOD group ovulation rate was 68.05% (196/288), pregnancy rate was 47.92% (23/48) The difference between the two groups was statistically significant (χ2 = 4.48, 4.94, P <0.05). Conclusion: The improvement of endocrine environment in six months after PCOS infertility LOD combined with tonifying kidney, invigorating spleen, expectorant and adjusting traditional Chinese medicine can improve ovulation rate and pregnancy rate of PCOS infertility patients.