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目的:探讨磷酸肌酸钠对急性期心肌梗死未行再灌注治疗患者心功能的影响。方法:急性期心肌梗死未行再灌注治疗患者71例,随机分为常规治疗组(n=29)及磷酸肌酸钠组(n=42),其中磷酸肌酸钠组在常规治疗基础上加用磷酸肌酸钠静脉滴注。应用超声心动图检测患者左室射血分数和左室内径大小,观察两组指标变化。结果:两组左室内径大小无统计学差异(t=-0.216,p=0.829),治疗组左室射血分数比对照组高(t=4.963,p=0.000)。结论:磷酸肌酸钠对急性期心肌梗死未行再灌注治疗心功能有保护作用。
Objective: To investigate the effect of sodium creatine phosphate on cardiac function in patients undergoing acute myocardial infarction without reperfusion. Methods: A total of 71 acute myocardial infarction patients without reperfusion were randomly divided into routine treatment group (n = 29) and sodium creatine phosphate group (n = 42). The sodium creatine phosphate group Phosphate creatinine intravenous infusion. The left ventricular ejection fraction and the left ventricular internal diameter were measured by echocardiography. The changes of the indexes in both groups were observed. Results: There was no significant difference in left ventricular diameter between the two groups (t = -0.216, p = 0.829). The left ventricular ejection fraction was higher in the treatment group than in the control group (t = 4.963, p = 0.000). CONCLUSION: Sodium creatine phosphate has a protective effect on cardiac function in acute myocardial infarction without reperfusion.