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目的调查健康老年男性的骨密度(BMD)变化规律并分析和原发性骨质疏松症(OP)相关的临床危险因素。方法在北京市朝阳区团结湖社区采用广告招募的抽样方法,对50岁以上健康老年男性接受自制《北京市老年男性原发性骨质疏松症高危人群临床危险因素调查问卷》调查的同时进行双能X线骨密度检查,记录腰椎总(L1-4)、左侧股骨颈(femoral neck)和左髋总(total hip)的BMD数值和年龄、体重、既往脆性骨折史、吸烟史、饮酒史等临床危险因素;根据世界卫生组织诊断标准将研究对象分为OP组和非OP组,分析各临床危险因素与OP发生的相关性。结果 518例老年男性总体OP患病率14.3%(74/518),骨量减少者53.7%(278/518),骨量正常者32.0%(166/518)。既往脆性骨折史、体重指数、体重在OP组和非OP间存在显著差异性(P<0.05)。结论社区健康老年男性OP患病情况不容乐观,低体重及低体重指数、既往脆性骨折史可能是OP相关的临床危险因素,有待于进一步深入研究。
Objective To investigate the changes of bone mineral density (BMD) in healthy elderly men and to analyze the clinical risk factors associated with primary osteoporosis (OP). Methods A sampling method of advertisement recruitment was adopted in Tuanjiehu community in Chaoyang District, Beijing. The survey of healthy elderly men over 50 years old receiving self-made questionnaire of clinical risk factors of high risk population of elderly men with primary osteoporosis in Beijing was conducted. X-ray bone mineral density was measured and BMD values of the lumbar spine (L1-4), left femoral neck and total hip were recorded, and their age, body weight, previous fragility fracture history, smoking history, drinking history And other clinical risk factors. According to the diagnostic criteria of WHO, the subjects were divided into OP group and non-OP group, and the correlation between each clinical risk factor and OP was analyzed. Results The overall prevalence of OP in 518 elderly men was 14.3% (74/518), the reduction of bone mass was 53.7% (278/518), and the normal bone mass was 32.0% (166/518). The history of previous fragility fractures, body mass index and body weight were significantly different between OP group and non-OP group (P <0.05). Conclusions The prevalence of OP in healthy elderly men in community is not optimistic, low body weight and low body mass index, and the history of previous fragility fracture may be the clinical risk factor related to OP, which needs to be further studied.