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目的对本地区的反流性食管炎的发病情况以及临床特征进行观察分析。方法选取我院2011年1月至2016年1月经过胃镜诊断确诊为反流性食管炎的患者500例,对患者的临床资料进行回顾性分析,观察总结本地区的反流性食管炎的发病情况以及临床特征。结果反流性食管炎患者占总胃镜检查人数的2.5%,其中男性375例(75%),女性125例(25%),患者年龄在14-85岁之间,其中60岁以上的患者180例(36%),60岁以下的患者320例(64%);对患者的严重程度进行分级,患者主要以轻度为主,临床症状以慢性咳嗽、咽部有异物感、胃灼烧感、反酸、胸骨后疼痛、上腹部隐痛为主;反流性食管炎的幽门螺杆菌阳性率低于受检人群,但轻度患者的幽门螺杆菌阳性率高于中、重度患者(P<0.05)。结论反流性食管炎的患者以轻度居多,中、重度患者以60岁以上年龄段居多,男性发病率高于女性,幽门螺杆菌感染可能对反流性食管炎病情的进展有一定的阻止作用。
Objective To observe and analyze the incidence and clinical features of reflux esophagitis in this area. Methods 500 cases diagnosed as reflux esophagitis by gastroscopy from January 2011 to January 2016 in our hospital were selected. The clinical data of the patients were retrospectively analyzed. The incidence of reflux esophagitis in our area was observed and summarized. Situation and clinical features. Results Reflux esophagitis patients accounted for 2.5% of the total number of gastroscopy, including 375 males (75%), 125 females (25%), patients aged 14-85 years, of which 180 patients over the age of 180 Cases (36%), 320 patients (64%) under 60 years of age; the severity of the patients were graded, the patients were mainly mild, clinical symptoms of chronic cough, foreign body sensation in the throat, heartburn , Acid reflux, post-sternal pain, upper abdominal pain; the positive rate of Helicobacter pylori in reflux esophagitis was lower than that of the subjects, but the positive rate of Helicobacter pylori in mild patients was higher than that in moderate and severe patients (P < 0.05). Conclusions The patients with reflux esophagitis are mostly mild, moderate and severe with the age of over 60 years old. The incidence of male is higher than that of female. Helicobacter pylori infection may prevent the progress of reflux esophagitis effect.