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目的了解新疆地区≥35岁人群代谢综合征(metabolic syndrome,MS)的患病情况和相关危险因素。方法采用多阶段分层随机抽样的方法,于2015年在新疆地区对3 644名35岁及以上常住居民进行调查,包括问卷调查、体格测量和实验室指标的检测。采用美国胆固醇教育计划成人治疗方案第三次报告(NCEP-ATP Ⅲ)诊断亚裔人群修订的版本作为MS的诊断标准,并通过2010年的人口学情况对其进行标化,采用非条件Logistic回归分析其影响因素。结果调查对象的MS患病率为26.40%(标化率为25.46%)。其中男性的患病率为24.66%(标化率为24.49%),女性为28.00%(标化率为26.18%)。在患有MS人群中,同时有中心性肥胖、血压异常和血脂异常三因素者占34.95%。维吾尔族的患病率最高,为41.18%。相对于无高血压家族史者,有高血压家族史人群患MS的风险更高(OR(95%CI):1.230(1.037~1.459),P=0.017)。结论新疆成年人MS患病率较高,高血压家族史是MS的危险因素。
Objective To investigate the prevalence and related risk factors of metabolic syndrome (MS) in people over 35 years of age in Xinjiang. Methods A multi-stage stratified random sampling method was used to survey 3 644 permanent residents aged 35 and above in the Xinjiang region in 2015, including questionnaires, physical measurements and laboratory tests. The third edition of the American Cholesterol Education Program Adult Treatment Program (NCEP-ATP III) was used to diagnose the revised version of the Asian population as a diagnostic criteria for MS and normalized to demographics by 2010 using non-conditional logistic regression Analyze its influencing factors. Results The prevalence of MS was 26.40% (standardization rate was 25.46%). Among them, the prevalence of males was 24.66% (standardization rate was 24.49%) and that of females was 28.00% (standardization rate was 26.18%). In MS population, there are 34.95% of the three factors including central obesity, abnormal blood pressure and dyslipidemia. The highest prevalence rate of Uighur was 41.18%. Patients with a family history of hypertension had a higher risk of developing MS (OR 95% CI: 1.230 (1.037-1.459, P = 0.017) relative to those with no family history of hypertension. Conclusion The morbidity of MS in Xinjiang adults is high, and the family history of hypertension is a risk factor for MS.