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目的探讨原发性肾脏弥漫性大B细胞淋巴瘤(DLBCL)的临床、病理特点及诊治方法。方法回顾分析1例原发性肾脏DLBCL患者的临床资料,结合国内外文献对DLBCL进行讨论。结果患者为22岁女性,无临床症状,无意中发现左上腹部肿块,术前诊断为左肾癌,行左肾根治性切除术,术后病理诊断为左肾DLBCL,行RCHOP方案治疗6次,患者一般状态良好,病情稳定。结论原发性肾脏DLBCL临床罕见,不易与肾癌鉴别,根据术后病理检查可确诊,患者预后较差,需联合化疗并长期随访。
Objective To investigate the clinical features and diagnosis and treatment of primary renal diffuse large B cell lymphoma (DLBCL). Methods The clinical data of one patient with primary renal DLBCL were retrospectively analyzed. DLBCL was discussed in combination with literature from home and abroad. Results The patient was 22 years old and had no clinical symptoms. The left upper abdomen was inadvertently found, the left kidney was diagnosed preoperatively, and the radical nephrectomy was performed. The left renal DLBCL was diagnosed postoperatively and was treated 6 times with RCHOP regimen. Patients generally in good condition, stable condition. Conclusion Primary renal DLBCL is clinically rare and not easily differentiated from renal cell carcinoma. According to the postoperative pathological examination, the prognosis is poor, requiring combined chemotherapy and long-term follow-up.