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目的:探讨宫腔镜子宫内膜息肉电切术(TCRP)联合去氧孕烯炔雌醇治疗子宫内膜息肉(EP)的临床效果。方法:选取2011年1月-2013年10月深圳市第二人民医院妇科收治的160例EP患者,于TCRP术后随机分为两组。其中观察组82例,术后口服去氧孕烯炔雌醇片,1片/d,连用21 d为1周期,连续治疗3个周期;对照组78例,术后不予任何治疗。随访12个月,观察两组患者在随访期间的子宫内膜息肉复发及月经变化情况。结果:对照组复发率12.82%,观察组患者复发率3.66%,差异有统计学意义(P<0.05)。两组治疗后月经量均减少,观察组月经量少于对照组,差异有统计学意义(P<0.05)。结论:TCRP联合去氧孕烯炔雌醇能有效减少EP复发并有利于改善月经状况。
Objective: To investigate the clinical effect of hysteroscopic endometrial polypectomy (TCRP) combined with desogestrel ethinyl estradiol in the treatment of endometrial polyps (EP). Methods: A total of 160 patients with EP who were admitted to Shenzhen Second People’s Hospital from January 2011 to October 2013 were randomly divided into two groups after TCRP. The observation group of 82 cases, after oral administration of desogestrel ethinyl estradiol tablets, 1 / d, once every 21 days for 1 cycle, continuous treatment for 3 cycles; control group of 78 patients without any treatment after surgery. The patients were followed up for 12 months. The recurrence and menstrual changes of endometrial polyps during the follow-up period were observed. Results: The recurrence rate was 12.82% in the control group and 3.66% in the observation group, the difference was statistically significant (P <0.05). The amount of menstruation in both groups decreased after treatment, and the amount of menstruation in the observation group was less than that in the control group (P <0.05). CONCLUSION: TCRP combined with desogestrel ethinyl estradiol can effectively reduce the recurrence of EP and improve the menstrual status.