我院自七四年八月开始应用三尖杉酯碱与高三尖杉酯碱混合物针剂于各种类型急性白血病,取得一定疗效。但也发现每批制剂在疗效上有一定差异。原因是每批针剂中三尖杉酯碱和高之三尖杉酯碱之间的比例无法取得每批都一致,因而临床疗效不稳定,为克服这一缺点,我们自第三次全国会议以后就着手进行单体分离工作。首先,摸索了薄层层离方法,找 Our hospital since August 74 began application of harringtonine and homoharringtonine mixture of injection in various types of acute leukemia and achieved a certain effect. But also found that there is a certain difference in the efficacy of each batch of preparation. The reason is that the ratio between harringtonine and homoharringtonine in each injection can not be obtained in the same batch and thus the clinical efficacy is not stable. To overcome this shortcoming, since the third national conference To proceed with monomer separation work. First of all, groping the layer separation method, find