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目的探讨静脉注射人血丙种球蛋白(IVIG)治疗小儿急性病毒性心肌炎的临床疗效。方法在对照组常规治疗的基础上加用IVIG作为治疗组,剂量为400 mg/(kg.d),连用5 d。结果治疗组患儿的心肌酶(CK、CK-MB、HBDH、cTnI)恢复时间、症状消失时间明显短于对照组,两组比较差异有统计学意义(P<0.05);治疗组心电图的改善优于对照组,两组比较差异有统计学意义(P<0.05)。结论 IVIG能较快改善急性病毒性心肌炎患儿的自觉症状、体征,恢复心肌酶、改善心电图,提示IVIG对心肌细胞有保护作用,可缩短急性病毒性心肌炎的治愈时间。
Objective To investigate the clinical efficacy of intravenous injection of human blood gamma globulin (IVIG) in children with acute viral myocarditis. Methods The routine treatment of the control group plus IVIG as the treatment group, a dose of 400 mg / (kg.d) for 5 d. Results The recovery time of myocardial enzymes (CK, CK-MB, HBDH, cTnI) and the disappearance of symptoms in the treatment group were significantly shorter than those in the control group, with significant difference between the two groups (P <0.05) The difference between the two groups was statistically significant (P <0.05). Conclusion IVIG can quickly improve the symptoms and signs of children with acute viral myocarditis, restore myocardial enzymes and improve the ECG, suggesting that IVIG can protect cardiomyocytes and shorten the cure time of acute viral myocarditis.