为探讨免疫应答在扁平苔藓发病过程中的作用及相互关系，本研究中应用ABC技术，用T3、T4、T8、IgG单抗及S－100蛋白标记病损已浸润细胞。结果表明：病损区以细胞免疫为主，淋巴细胞数量与上皮钉突的增殖程度呈正相关；病损区中郎罕氏细胞明显偏高；基底膜区损害与T细胞数量呈正相关；IgG阳性细胞散在分布于病损区，其阳性物质在基底膜区沉积。提示该疾病以细胞免疫为主，同时有体液免疫应答的参与。 In order to investigate the role and relationship of immune response in the pathogenesis of lichen planus, ABC technique was used in this study to label the lesion infiltrating cells with T3, T4, T8, IgG monoclonal antibody and S-100 protein. The results showed that the cellular immunity was predominant in the lesion area, the number of lymphocytes was positively correlated with the proliferation of epithelial nail, the number of Langerhans cells in the lesion area was significantly higher, the damage of basement membrane area was positively correlated with the number of T cells, Cells scattered in lesion area, the positive material deposition in the basement membrane area. Suggesting that the disease is mainly cellular immunity, while humoral immune response involved.