Franceschetti Klein 综合征又称多发性面部异常综合征、双侧面部发育不全等,临床罕见,现报道一例。患儿谢某,男,6岁,因面部先天畸形要求整容入院。其母孕期有感染发热史,否认用药史,非近亲婚配,第一、二代直系亲属中无类似病史。检查:全身情况尚好,未见异常。面部多发性畸形,双侧面斜裂,皮肤凹 Franceschetti Klein syndrome, also known as multiple facial syndrome, bilateral facial hypoplasia, clinically rare, is reported in one case. Children Xiemou, male, 6 years old, due to facial congenital malformations require cosmetic admission. The mother had a history of fever during pregnancy, denied medication history, non-relatives marriage, the first and second generation of immediate family members without a similar history. Check: the whole body is still good, no exception. Facial multiple deformities, bilateral oblique crack, the skin concave