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在见于急性粒细胞性白血病(AML)和偶见于骨髓增殖症(MDS)的t(8;21)(q22;q22),其结果导致22q22上的AML_1基因与8q22上的ETO基因相融合,产生嵌合AML_1/ETO转录产物,它是一种易位的分子标记物。
As a result, t (8; 21) (q22; q22) occasionally seen in acute myelogenous leukemia (AML) and myeloproliferative disorder (MDS) resulted in the fusion of the AML_1 gene on 22q22 with the ETO gene on 8q22 Chimeric AML_1 / ETO transcript, a translocation marker.