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目的:比较在相同患者中杂交置入的CYPHER和TAXUS支架术后再狭窄的比率,以排除患者因素对再狭窄的影响,判定2种支架再狭窄率的真实差别。方法:回顾性分析2004年4月~2006年4月于北京阜外医院接受杂交置入并完成6个月造影随访的患者101例,其中CYPHER支架170枚,TAXUS支架138枚,据此分成2组。结果:2组基线病变的特点差异无统计学意义。CYPHER组支架内和病变血管段再狭窄率均低于TAXUS组(分别为:5.2%∶12.8%,P<0.05;6.5%∶15.4%,P<0.05),最小管腔直径和晚期管腔丢失CY-PHER组也明显低于TAXUS组[分别为:(2.01±0.02)∶(1.96±0.03)mm,P<0.01;(0.11±0.04)∶(0.31±0.02)mm,P<0.01]。结论:CYPHER支架再狭窄率低于TAXUS支架。
OBJECTIVE: To compare the rate of restenosis after CYPHER and TAXUS stenting in the same patient in order to exclude the influence of patient factors on restenosis, and to determine the true difference between the two stent restenosis rates. Methods: A retrospective analysis of 101 patients who underwent hybridization in Beijing Fuwai Hospital from April 2004 to April 2006 with 6-month angiographic follow-up was performed. Among them, CYPHER stent was 170 and TAXUS stent was 138, which were divided into 2 group. Results: There was no significant difference between the two groups in baseline characteristics. The restenosis rates in the stent and lesion vascular segments in the CYPHER group were lower than those in the TAXUS group (5.2% vs12.8%, P <0.05; 6.5% vs15.4%, P <0.05, respectively), and the smallest lumen diameter and late lumen loss The CY-PHER group was also significantly lower than the TAXUS group [(2.01 ± 0.02) vs. (1.96 ± 0.03) mm, P <0.01; (0.11 ± 0.04) vs. (0.31 ± 0.02) mm, P <0.01; Conclusion: CYPHER stent restenosis rate is lower than that of TAXUS stent.