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以邻氟苯胺为起始原料,经酰化、氯化、水解制得4-氯-2-氟苯胺,再经重氮化,还原反应合成标题化合物,产品收率87.1%,m.p.59～60℃。该方法步骤简单易操作、反应条件温和、产品收率高、纯度好,适合工业化生产。产品通过红外光谱进行了结构鉴定。
O-fluoroaniline as the starting material, acylation, chlorination, hydrolysis 4-chloro-2-fluoroaniline, and then by diazotization, reduction reaction synthesis of the title compound, the yield of 87.1%, mp 59 ~ 60 ℃. The method has the advantages of simple and easy operation, mild reaction conditions, high product yield and good purity, and is suitable for industrialized production. The product was identified by infrared spectroscopy.