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细胞凋亡的过程涉及一系列凋亡相关分子的调控。这些凋亡相关分子在机体中的异常调节将导致包括肿瘤和免疫性疾病在内的多种疾病的发生。针对凋亡相关分子的治疗策略在肿瘤治疗中具有重要意义。本文以细胞凋亡相关分子及其在肿瘤基因治疗中的应用研究做一综述,为肿瘤治疗提供新的策略。
The process of apoptosis involves the regulation of a series of apoptosis-related molecules. Abnormal regulation of these apoptosis-related molecules in the body will lead to the occurrence of various diseases including tumor and immune diseases. Therapeutic strategies targeting apoptosis-related molecules are of great importance in cancer therapy. In this review, we summarize apoptosis-related molecules and their applications in the gene therapy of cancer, and provide a new strategy for the treatment of cancer.