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妊娠期间胎儿与母亲同呼吸,共命运,为了胎儿的发育健康,此间用药要特别小心谨慎。许多条件能影响药物通过胎盘的速度和量,因而产生不同的后果。这些条件有:⑴药物的理化性质,如药物的脂溶性不小,脂溶性药物易通过胎盘;药物的Pka,通常弱碱性药物易通过胎盘,而弱酸性药物则不易通
During pregnancy, fetus and mother with the same breath, a total of fate, in order to develop the health of the fetus during the medication to be particularly cautious. Many conditions can affect the speed and amount of drug passing through the placenta, resulting in different consequences. These conditions are: ⑴ physical and chemical properties of drugs, such as fat-soluble drugs is not small, fat-soluble drugs easily through the placenta; drug Pka, usually weak alkaline drugs easily through the placenta, and weak acid drugs are not easy to pass