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目的:探讨玻璃体腔注射曲安奈德(TA)治疗各种疾病引起的黄斑水肿的疗效。方法:对18例18眼黄斑水肿患者,采用玻璃体腔注射曲安奈德进行治疗,术后3d、1周、1月检查裸眼及最佳矫正视力、眼压、行眼底照相、眼底荧光血管造影(FFA)眼底检查和光相干断层扫描(OCT)检查。OCT观察黄斑中心凹平均厚度。结果:所有患者中,18眼有16眼视力有提高,2眼视力无明显提高,总有效率88.9%,黄斑中心凹厚度在术前为(525.0±70.5)μm,而随访1月后最终黄斑厚度平均为(452.0±62.5)μm,差异有统计学意义(P<0.05)。无视网膜脱离、眼内出血、感染性眼内炎及其他并发症发生。结论:通过OCT对黄斑部的观察和定量分析,可看出曲安奈德玻璃体腔注射对于各种原因引起的黄斑水肿有较明显的疗效。
Objective: To investigate the efficacy of intravitreal injection of triamcinolone acetonide (TA) in the treatment of various diseases caused by macular edema. Methods: Eighteen patients with macular edema were treated with vitreous cavity injection of triamcinolone acetonide. The naked eyes and best corrected visual acuity, intraocular pressure, fundus photography and fundus fluorescein angiography FFA) fundus examination and optical coherence tomography (OCT) examination. OCT observed macular foveal average thickness. Results: In all patients, visual acuity was improved in 16 eyes and no visual acuity in 2 eyes, the total effective rate was 88.9%. The foveal thickness of the foveal was (525.0 ± 70.5) μm preoperatively, and the final macular thickness The average thickness was (452.0 ± 62.5) μm, the difference was statistically significant (P <0.05). No retinal detachment, intraocular hemorrhage, infectious endophthalmitis and other complications occurred. CONCLUSIONS: Observation and quantitative analysis of the macula by OCT showed that triamcinolone acetonide intravitreal injection has a significant effect on macular edema caused by various causes.