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人血清甲状腺素结合容量的测定,可间接反映血循环中甲状腺激素结合球蛋白的浓度,它与血清总甲状腺激素(T_3、T_4)测定相配合,可求得游离甲状腺激素指数(FT_3I,FT_4I),以提高甲状腺功能体外方法诊断的准确性。所用的~(125)I-T_3吸附剂最早采用红细胞法,后又发展了树脂法、凝胶法和炭末法,这些方法虽然结果尚称可靠,但有的使用不够方便,或有的操作时间较长。近年国外采用大颗粒白蛋白(MAA)作为吸附剂,方法简便、快速、稳定,且用血量少。1979年英国放射化学中心已有商品药盒供应。1980年我们进行~(125)I-T_3 MAA摄取试验及其影响的观察,今将初步结果作一简要报导。
The determination of thyroxine binding capacity of human serum can indirectly reflect the concentration of thyroid hormone-binding globulin in the blood circulation. It can be used to determine the free thyroid hormone index (FT_3I, FT_4I) in combination with the determination of serum total thyroid hormone (T_3, T_4) To improve the diagnostic accuracy of thyroid function in vitro methods. The earliest use of ~ (125) I-T_3 adsorbent is the red cell method, and then the resin method, gel method and carbon powder method are developed. Although these methods are still reliable, some methods are inconvenient to use or have some operation time Longer. In recent years, foreign use of large particles of albumin (MAA) as an adsorbent, the method is simple, fast, stable, and with less blood. In 1979, the Radiochemical Center of the United Kingdom already had a supply of commercial kits. In 1980 we conducted ~ 125 I-T 3 MAA uptake and its impact on the observation, the preliminary results will now be a brief report.