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实验村社区居民钩虫感染率为52.2%,其中美洲钩虫感染占96%,159个居民的美洲钩虫平均虫负荷为2.8条。用数学模型算得的种群动力学参数负二项分布值(K)、密度依赖限制值(Z)、和基本繁殖率(R)值分别为0.52、0.907和1.854,美洲钩虫感染者经药物治疗后第4、7和12个月的再感染率分别为5.0%、9.2%和15.1%,再感染者的修正EPG值分别为140,144和164。理论感染率分别为22.7%、34.2%和42.8%,理论平均虫负荷数分别是0.254、0.528和0.926条,据此认为,单纯运用化疗措施来控制和消灭美洲钩虫流行的效果不理想。
The infection rate of Hookworm in experimental community was 52.2%, of which Hookworm infection was 96%. The average worm burden of American hookworm with 159 inhabitants was 2.8. The negative binomial distribution (K), density-dependent limit (Z) and basic reproductive rate (R) of the population dynamics parameters calculated by the mathematical model were 0.52, 0.907 and 1.854, respectively. The rates of re-infection at the 4th, 7th, and 12th months were 5.0%, 9.2% and 15.1%, respectively. The revisited EPG values were 140,144 and 164 respectively. The theoretical infection rates were 22.7%, 34.2% and 42.8%, respectively. The theoretical average worm burden was 0.254, 0.528 and 0.926, respectively. Therefore, the effect of using chemotherapy alone to control and eliminate the prevalence of hookworm was not satisfactory.