男性勃起功能障碍(ED)是男科常见疾病之一,当前全世界有15200万男性受到ED的困扰。近年来已经认识到活性氧(reactive oxygen species,ROS)在ED中起重要作用。本文总结近年来ROS在ED中作用的研究进展,并阐述ROS与ED中各种危险因子的关系以及抗氧化治疗进展,为开发治疗ED的药物提供新的方向。 Male erectile dysfunction (ED) is one of the most common diseases in men and women. Currently, 152 million men in the world are plagued by ED. In recent years, it has been recognized that reactive oxygen species (ROS) play an important role in ED. This article summarizes the research progress of the role of ROS in ED in recent years, and expounds the relationship between ROS and various risk factors in ED as well as the progress of anti-oxidative therapy, providing a new direction for the development of drugs for the treatment of ED.