结肠肝曲癌可侵犯十二指肠降部,形成恶性结肠—十二指肠瘘。由于十二指肠降部的解剖特点,给手术切除带来困难,常被迫行姑息性手术。最近,我们为两例恶性结肠—十二指肠瘘患者进行了右半结肠切除和受侵的十二指肠降部前壁切除术,用带血管蒂的全层回肠片修补十二指肠降部巨大缺损,获得成功。 Liver cancer of the colon can invade the descending part of the duodenum and form a malignant colon-duodenal fistula. Due to the anatomical characteristics of the descending duodenum, it is difficult to remove the tumor and is often forced to undergo palliative surgery. Recently, we performed right hemicolectomy and anterior wall resection of the affected descending duodenum in two patients with malignant colon-duodenal fistula. The duodenum was repaired with a vascularized full-thickness ileal slice. A huge defect in the descending area was successful.