本文以丙酮丁醇连续发酵过程为背景,提出了一类微生物混合生长模型。对此模型进行仿真,可确定在连续发酵系统中使用的各枝(批)菌株的实际操作周期,继而通过物料衡算计算出该菌株的得率。菌株得率的实时计算是连续发酵过程中进行菌株筛选的基础。各菌株得率的高低可被用作评判其优劣的标准,并可据此指导实际生产过程中的菌株选用,以达降低原料消耗的目的。 In this paper, acetone-butanol continuous fermentation process as a background, put forward a mixed microbial growth model. The model was simulated to determine the actual operating cycle of each batch of batches used in a continuous fermentation system, and the yield of the strain was calculated by material balance. Real-time calculation of strain yield is the basis for strain selection during continuous fermentation. The yield of each strain can be used as a criterion for judging its advantages and disadvantages, and can guide the actual selection of strains in the production process, in order to achieve the purpose of reducing raw material consumption.