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目的 评价中晚期原发性肝癌各种疗法的效果。方法 104例中手术治疗51例(行肿瘤切除26例,冷冻治疗15例,肝动脉和门静脉置泵化疗8例,肿瘤无水酒精注射2例)。放射介入行肝动脉插管栓塞53例。结果 手术组手术死亡2例。随访93例(9327%)。各种治疗后1,2年生存率分别为:肿瘤切除者为50%和308%;冷冻治疗者533%和20%;肝动脉和门静脉全埋入式药泵置入者375%和125%;经股动脉肝动脉插管化疗栓塞者为321%和151%;2例行肿瘤无水酒精注射者均在1年死亡。结论 手术切除仍是肝癌首选和最有效的治疗;亦可通过冷冻治疗,其疗效明显优于化疗栓塞术。
Objective To evaluate the effect of various therapies in advanced primary liver cancer. Methods Totally 51 cases underwent surgical resection in 104 cases (tumor resection in 26 cases, cryotherapy in 15 cases, hepatic artery and portal vein in pump chemotherapy in 8 cases and tumor anhydrous ethanol injection in 2 cases). Radiotherapy interventional hepatic artery embolism in 53 cases. Results The operation group died of surgery in 2 cases. Follow-up 93 cases (9327%). The 1-year and 2-year survival rates of the various treatments were 50% and 308% for tumor resection, 533% and 20% for cryotherapy, 375% and 125% for all implanted pump of hepatic artery and portal vein, ; 321% and 151% were transcatheter arterial chemoembolization through the femoral artery; 2 patients died of cancer alcohol injection in one year. Conclusions Surgical resection is still the first choice and the most effective treatment for liver cancer. It can also be treated by cryotherapy, and the curative effect is better than that of chemoembolization.