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目的:分析非小细胞肺癌的临床病理特点与预后的相关因素。方法:应用SPSS软件回顾分析80例获得随访资料的非小细胞肺癌患者的预后相关因素。结果:(1)TNM分期、Ki-67标记指数以及微血管密度是预后的独立危险因素。(2)耐药基因GST-π和病理类型是预后的相对危险因素。(3)患者年龄、性别、病程长短、肿瘤大小、部位、有无坏死与预后无显著相关。结论:TNM分期是非小细胞肺癌最重要的预后独立指标,其次为Ki-67标记指数、微血管密度,而肿瘤耐药基因GST-π和病理类型则是预后相对指标。
Objective: To analyze the clinicopathological features and prognostic factors of non-small cell lung cancer. Methods: SPSS software was used to retrospectively analyze the prognostic factors of 80 patients with follow-up data of non-small cell lung cancer. Results (1) TNM staging, Ki-67 labeling index and microvessel density were independent prognostic risk factors. (2) Resistance gene GST-π and pathological type are the relative risk factors of prognosis. (3) The patient’s age, sex, duration of disease, tumor size, location, presence or absence of necrosis and prognosis had no significant correlation. Conclusion: TNM staging is the most important independent prognostic factor for non-small cell lung cancer, followed by Ki-67 labeling index and microvessel density, while the tumor resistance gene GST-π and pathological type are relative prognostic indicators.