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目的:探究重症手足口病患儿心肌酶,c Tn I和hs-CRP的检测意义。方法:将300例重症手口足并患者设为重症组,同期同数量300例普通手口足病患者为对照组,将两组患者的心肌酶,c Tn I和hs-CRP进行检测,同时分析重症组治疗前后上述指标变化。结果:重症组的c Tn I和hsCRP,心肌酶参数明显比对照组高,组间数据存在统计学意义,P<0.05;重症组上述指标均体现出下降趋势P<0.05.结论:对手足口病患者心肌酶、肌钙蛋白Ⅰ和超敏C-反应蛋白进行联合检测,能够体现出患者心肌损害和炎性反应严重程度,对早期诊断,干预和预后有着重要的临床意义。
Objective: To investigate the significance of myocardial enzymes, cTn I and hs-CRP in children with severe hand-foot-mouth disease. Methods: Three hundred patients with severe hand and mouth were selected as severe group. The same amount of 300 common hand-foot-pod patients were used as control group during the same period. The myocardial enzymes, cTn I and hs-CRP in both groups were detected, Before and after treatment, the above indexes changed. Results: The indexes of cTn I, hsCRP and myocardial enzymes in severe group were significantly higher than those in control group, the data of the two groups were statistically significant (P <0.05), and all the above indexes in the severe group showed a decreasing trend P <0.05.Conclusion: Patients with myocardial enzymes, troponin Ⅰ and high sensitivity C-reactive protein joint detection, can reflect the severity of myocardial damage and inflammatory reactions in patients with early diagnosis, intervention and prognosis has important clinical significance.