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目的评价丝蛋白创面敷料治疗Ⅱ度烧伤创面的临床疗效与安全性。方法 48例Ⅱ度烧伤患者随机均分为治疗组(用丝蛋白创面敷料覆盖,B组)及对照组(用灭菌凡士林纱布覆盖,A组),观察创面愈合时间、创面边缘炎性反应程度和疼痛程度。结果与A组比较,B组创面愈合时间短、疼痛程度评分低(P<0.01);两组炎性反应程度评分差异无统计学意义(P>0.05)。结论丝蛋白创面敷料能明显促进Ⅱ度创面的愈合。
Objective To evaluate the clinical efficacy and safety of silk fibroin wound dressing in the treatment of second degree burn wounds. Methods Forty-eight patients with grade Ⅱ burn were randomly divided into treatment group (covered with silk fibroin wound dressing, group B) and control group (covered with sterilized vaseline gauze, group A). The wound healing time, degree of inflammatory reaction And the degree of pain. Results Compared with group A, the wound healing time of group B was shorter and the pain score was lower (P <0.01). There was no significant difference in inflammatory response between two groups (P> 0.05). Conclusion silk fibroin wound dressing can significantly promote the healing of degree Ⅱ wound.