我院急诊科 2002至 2003年收治 2例以疼痛为首发症状的药物过敏性休克,报道如下。例 1　男, 40岁,龋齿拔牙术后,常规抗感染治疗,青霉素皮试(皮试液含青霉素 200U/ml)阴性后,予青霉素 800万U加入生理盐水 250ml静脉滴注, 15min后,滴入约 50ml,患者自述注射部位疼痛,但无皮痒 Emergency Department of our hospital from 2002 to 2003 admitted 2 cases of pain as the first symptom of drug allergic shock, reported as follows. Example 1 Male, 40 years old, tooth decay after dental caries, routine anti-infective treatment, penicillin skin test (skin test solution containing penicillin 200U / ml) negative to penicillin 800 million U 250ml normal saline intravenously, 15min after the drop Into about 50ml, the patient described the injection site pain, but no itchy skin