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目的:目前对肺腺癌脑转移瘤治疗前后病灶强化采用MRI影像技术进行对比,并对脑内转移灶放疗疗效进行评估。方法:选取2013年1月至2015年1月该院所确诊肺腺癌脑转移瘤患者13例,其中脑转移灶共44个。在放疗前3~4 w、放疗后3~4 w及18~24 w,对患者采用MRI常规检测与强化检测,对患者病灶强化后增强比及时间变化进行检测,并同强化后37s状态加以对比。结果:放疗前44个病灶在37 s状态时的信号强度平均上升(71±19)%,放疗后3~4 w病灶信号强度平均上升(34±10)%,放疗后18~24 w病灶信号强度平均上升(13±4)%。结论:在肺腺癌转移瘤放疗治疗中,药动力学MRI影像技术可以对放疗治疗效果进行有效评估,为临床提供科学而准确的治疗依据。
OBJECTIVE: To compare MRI imaging before and after the treatment of brain metastases of lung adenocarcinoma and to evaluate the efficacy of radiotherapy in metastatic brain tumors. Methods: From January 2013 to January 2015, 13 patients with brain adenocarcinoma of brain metastases diagnosed in our hospital were selected, including 44 brain metastases. In 3 ~ 4 w before radiotherapy, 3 ~ 4 w and 18 ~ 24 w after radiotherapy, the patients were examined by routine MRI and intensified test, and the enhancement ratio and time change after lesion enhancement were detected, Compared. Results: The average signal intensity of 44 lesions increased by 71 ± 19% at 37 s before radiotherapy, 34 ± 10% at 3 ~ 4 w after radiotherapy, and 18-24 w lesions after radiotherapy The average intensity increased by (13 ± 4)%. Conclusion: In the treatment of metastatic adenocarcinoma of the lung adenocarcinoma, pharmacokinetic MRI imaging can effectively evaluate the effect of radiotherapy and provide scientific and accurate basis for clinical treatment.